| 1. Round | 12/02/2022 | Banfield II | - | San Lorenzo II | 2:1 | ||||
| 2. Round | 16/02/2022 | Sarmiento de Junín II | - | Banfield II | 0:1 | ||||
| 4. Round | 27/02/2022 | Platense II | - | Banfield II | 1:2 | ||||
| 5. Round | 04/03/2022 | Banfield II | - | Defensa y Justicia II | 2:0 | ||||
| 7. Round | 17/03/2022 | Lanús II | - | Banfield II | 1:1 | ||||
| 8. Round | 04/04/2022 | Banfield II | - | Argentinos Juniors II | 1:0 | ||||
| 9. Round | 08/04/2022 | Patronato de Paraná II | - | Banfield II | 0:2 | ||||
| 10. Round | 14/04/2022 | Banfield II | - | River Plate II | 2:3 |  |
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| 11. Round | 19/04/2022 | Newell's Old Boys II | - | Banfield II | 1:0 | ||||
| 13. Round | 02/05/2022 | Racing Club II | - | Banfield II | 2:0 | ||||
| 14. Round | 06/05/2022 | Banfield II | - | Atlético Tucumán II | 3:4 |  |
Argentina