| 1. Round | 18/07/2021 | Kvant Obninsk | - | FK Saturn | 2:1 | ||||
| 2. Round | 25/07/2021 | FK Khimki 2 | - | Kvant Obninsk | 2:0 | ||||
| 10. Round | 14/09/2021 | Kvant Obninsk | - | FK Peresvet Podolsk | 1:3 | ||||
| 11. Round | 18/09/2021 | Metallurg Vidnoye | - | Kvant Obninsk | 2:1 | ||||
| 12. Round | 26/09/2021 | Kvant Obninsk | - | FK Khimki 2 | 0:0 | ||||
| 13. Round | 30/09/2021 | Kvant Obninsk | - | FK Strogino Moskva | 1:2 | ||||
| 14. Round | 04/10/2021 | SKA-Khabarovsk 2 | - | Kvant Obninsk | 3:0 | ||||
| 15. Round | 10/10/2021 | FK Znamya Noginsk | - | Kvant Obninsk | 1:1 | ||||
| 16. Round | 14/10/2021 | Kvant Obninsk | - | FK Saransk | 1:4 | ||||
| 18. Round | 25/10/2021 | FK Kolomna | - | Kvant Obninsk | 0:2 | ||||
| 19. Round | 31/10/2021 | Kvant Obninsk | - | Rodina Moskva | 1:2 | ||||
| 21. Round | 11/11/2021 | Kvant Obninsk | - | Metallurg Vidnoye | 2:2 | ||||
| 22. Round | 14/11/2021 | FK Saturn | - | Kvant Obninsk | 2:1 | ||||
| 5. Round | 17/11/2021 | Kvant Obninsk | - | FK Znamya Noginsk | 1:1 |
Russia