| 1. Round | 22/08/2020 | Paphos FC | - | Omonia Nikosia | 2:2 | ||||
| 2. Round | 30/08/2020 | Omonia Nikosia | - | Karmiotissa Polemidion | 1:0 | ||||
| 3. Round | 12/09/2020 | Anorthosis Famagusta | - | Omonia Nikosia | 1:1 | ||||
| 6. Round | 04/10/2020 | Omonia Nikosia | - | AEL Limassol | 3:0 | ||||
| 7. Round | 18/10/2020 | Ethnikos Achna | - | Omonia Nikosia | 1:2 | ||||
| 11. Round | 22/11/2020 | Nea Salamina | - | Omonia Nikosia | 2:1 | ||||
| 14. Round | 14/12/2020 | Omonia Nikosia | - | Paphos FC | 2:1 | ||||
| 15. Round | 18/12/2020 | Karmiotissa Polemidion | - | Omonia Nikosia | 1:5 | ||||
| 20. Round | 16/01/2021 | Omonia Nikosia | - | Ethnikos Achna | 2:0 | ||||
| 21. Round | 23/01/2021 | Enosis Neon Paralimni | - | Omonia Nikosia | 0:1 | ||||
| 22. Round | 29/01/2021 | Omonia Nikosia | - | Olympiakos Nikosia | 1:1 | ||||
| 25. Round | 13/02/2021 | Ermis Aradippou | - | Omonia Nikosia | 0:2 |
Portugal