| 2. Round | 18/08/2021 | FC Basel 1893 II | - | FC Bavois | 2:3 | ||||
| 4. Round | 28/08/2021 | FC Basel 1893 II | - | AC Bellinzona | 2:1 | ||||
| 5. Round | 04/09/2021 | FC Basel 1893 II | - | BSC Young Boys II | 5:2 | ||||
| 7. Round | 22/09/2021 | FC Biel/Bienne | - | FC Basel 1893 II | 1:1 | ||||
| 10. Round | 09/10/2021 | Etoile Carouge FC | - | FC Basel 1893 II | 2:1 |  |
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| 11. Round | 16/10/2021 | FC Basel 1893 II | - | FC Zürich II | 1:1 | ||||
| 12. Round | 23/10/2021 | FC Breitenrain Bern | - | FC Basel 1893 II | 2:1 | ||||
| 13. Round | 30/10/2021 | FC Basel 1893 II | - | SC Brühl | 1:3 | ||||
| 14. Round | 06/11/2021 | SC YF/Juventus Zürich | - | FC Basel 1893 II | 6:0 | ||||
| 15. Round | 13/11/2021 | FC Basel 1893 II | - | SC Cham | 3:4 | ||||
| 16. Round | 20/11/2021 | FC Basel 1893 II | - | FC Black Stars Basel | 0:1 | ||||
| 17. Round | 27/11/2021 | FC Bavois | - | FC Basel 1893 II | 2:0 |
Brazil