| Group H | 05/06/2021 | Cascavel FC - PR | - | Joinville - SC | 3:3 | ||||
| Group H | 24/07/2021 | Cascavel FC - PR | - | Rio Branco - PR | 3:1 | ||||
| Group H | 07/08/2021 | Esportivo - RS | - | Cascavel FC - PR | 2:2 | ||||
| Group H | 14/08/2021 | Cascavel FC - PR | - | Aimoré - RS | 2:2 | ||||
| Group H | 21/08/2021 | S.E.R. Caxias - RS | - | Cascavel FC - PR | 1:1 | ||||
| Group H | 04/09/2021 | Joinville - SC | - | Cascavel FC - PR | 3:1 | ||||
| Round of 32 | 12/09/2021 | Cianorte - PR | - | Cascavel FC - PR | 0:0 | ||||
| Round of 32 | 18/09/2021 | Cascavel FC - PR | - | Cianorte - PR | 0:3 |  |
Brazil