| 3. Round | 06/03/2022 | Mito HollyHock | - | Blaublitz Akita | 0:1 | ||||
| 1. Round | 09/03/2022 | Oita Trinita | - | Mito HollyHock | 1:1 | ||||
| 4. Round | 13/03/2022 | Yokohama FC | - | Mito HollyHock | 3:2 |  |
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| 5. Round | 19/03/2022 | FC Ryūkyū | - | Mito HollyHock | 1:2 | ||||
| 6. Round | 26/03/2022 | Mito HollyHock | - | Roasso Kumamoto | 2:0 | ||||
| 7. Round | 30/03/2022 | Mito HollyHock | - | Tochigi SC | 0:1 | ||||
| 8. Round | 03/04/2022 | Thespakusatsu Gunma | - | Mito HollyHock | 2:1 | ||||
| 9. Round | 10/04/2022 | Zweigen Kanazawa | - | Mito HollyHock | 1:1 | |
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| 10. Round | 17/04/2022 | Mito HollyHock | - | Tokushima Vortis | 1:1 | ||||
| 11. Round | 23/04/2022 | Mito HollyHock | - | Renofa Yamaguchi | 3:2 | ||||
| 12. Round | 27/04/2022 | V-Varen Nagasaki | - | Mito HollyHock | 1:0 | ||||
| 16. Round | 14/05/2022 | Tokyo Verdy | - | Mito HollyHock | 0:2 | ||||
| 19. Round | 29/05/2022 | JEF United Chiba | - | Mito HollyHock | 2:1 | ||||
| 20. Round | 05/06/2022 | RB Omiya Ardija | - | Mito HollyHock | 0:2 | ||||
| 23. Round | 25/06/2022 | Mito HollyHock | - | Fagiano Okayama | 1:1 | ||||
| 28. Round | 23/08/2022 | Mito HollyHock | - | Oita Trinita | 2:0 |
Japan