| 1. Round | 07/08/2005 | FK SIAD Most | - | FK Teplice | 2:1 |  |
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| 2. Round | 13/08/2005 | AC Sparta Praha | - | FK SIAD Most | 2:1 | |
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| 3. Round | 22/08/2005 | FK SIAD Most | - | Baník Ostrava | 4:0 | ||||
| 4. Round | 27/08/2005 | 1. FC Slovácko | - | FK SIAD Most | 2:1 | |
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| 5. Round | 11/09/2005 | FK SIAD Most | - | Chmel Blsany | 3:1 | ||||
| 6. Round | 18/09/2005 | Vysočina Jihlava | - | FK SIAD Most | 1:0 | ||||
| 7. Round | 26/09/2005 | FK SIAD Most | - | Sigma Olomouc | 0:2 | ||||
| 8. Round | 02/10/2005 | Viktoria Plzeň | - | FK SIAD Most | 2:1 | |
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| 11. Round | 30/10/2005 | FK SIAD Most | - | Tescoma Zlín | 0:0 | ||||
| 12. Round | 06/11/2005 | FK Mladá Boleslav | - | FK SIAD Most | 1:0 | ||||
| 13. Round | 20/11/2005 | FK SIAD Most | - | FK Marila Příbram | 1:0 | ||||
| 14. Round | 26/11/2005 | FK SIAD Most | - | Slovan Liberec | 1:2 | |
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| 16. Round | 12/12/2005 | FK SIAD Most | - | AC Sparta Praha | 0:3 |
Czech Republic