| Serie B | Matches | W | D | L |  |
 |
 |
| home | 1 | 1 | - | - | 4 | - | 1 |
| away | 3 | - | 3 | - | 9 | - | - |
| overall | 4 | 1 | 3 | - | 13 | - | 1 |
| Serie B | Home | - | Guest | |
|
|
Results |
| 22/07/21 | Atlético Porteño | - | Atlético Santo Domingo | 1 | - | - | 0:0 |
| 01/09/21 | Atlético Santo Domingo | - | Cumbayá | 4 | - | 1 | 2:1 |
| 22/07/22 | Olmedo | - | Atlético Santo Domingo | 5 | - | - | 1:1 |
| 16/09/22 | Manta | - | Atlético Santo Domingo | 3 | - | - | 0:0 |
Ecuador