| Copa Libertadores | Matches | W | D | L |  |
 |
 |
| home | 2 | - | 1 | 1 | 5 | - | - |
| away | 2 | - | 1 | 1 | 10 | - | - |
| overall | 4 | - | 2 | 2 | 15 | - | - |
| Copa Sudamericana | Matches | W | D | L | |
|
|
| home | 2 | 1 | - | 1 | 2 | - | - |
| away | 2 | 1 | - | 1 | 4 | - | - |
| overall | 4 | 2 | - | 2 | 6 | - | - |
| Copa Libertadores | Home | - | Guest | |
|
|
Results |
| 18/03/03 | Universidad Católica | - | Cerro Porteño | 5 | - | - | 2:1 |
| 15/02/06 | Cerro Porteño | - | Palmeiras | 3 | - | - | 0:0 |
| 15/04/11 | Cerro Porteño | - | Santos FC | 2 | - | - | 1:2 |
| 14/03/14 | O'Higgins | - | Cerro Porteño | 5 | - | - | 2:2 |
| Copa Sudamericana | Home | - | Guest | |
|
|
Results |
| 20/08/09 | La Paz FC | - | Cerro Porteño | 1 | - | - | 1:2 |
| 09/08/12 | Cerro Porteño | - | O'Higgins | - | - | - | 4:0 |
| 09/11/12 | Tigre | - | Cerro Porteño | 3 | - | - | 4:2 |
| 06/11/14 | Cerro Porteño | - | Boca Juniors | 2 | - | - | 1:4 |
Uruguay