| Primera División | Matches | W | D | L |  |
 |
 |
| home | 4 | 2 | 1 | 1 | 6 | 2 | 2 |
| away | 7 | 4 | 1 | 2 | 21 | - | - |
| overall | 11 | 6 | 2 | 3 | 27 | 2 | 2 |
| Primera División | Home | - | Guest | |
|
|
Results |
| 14/03/10 | CF Pachuca | - | Santos Laguna | 2 | - | - | 0:3 |
| 12/09/10 | Gallos Blancos (old) | - | Santos Laguna | 3 | - | - | 5:2 |
| 16/01/11 | Pumas UNAM | - | Santos Laguna | 2 | - | - | 2:0 |
| 24/07/11 | CF Pachuca | - | Santos Laguna | 3 | - | - | 1:4 |
| 25/09/11 | Puebla FC | - | Santos Laguna | 5 | - | - | 1:2 |
| 08/01/12 | Santos Laguna | - | CF Pachuca | 2 | 1 | - | 0:0 |
| 26/01/13 | Santos Laguna | - | Club León | 3 | - | - | 2:0 |
| 25/01/14 | Gallos Blancos | - | Santos Laguna | 4 | - | - | 0:0 |
| 20/07/14 | CD Veracruz | - | Santos Laguna | 2 | - | - | 0:1 |
| 26/07/15 | Santos Laguna | - | Club León | 1 | 1 | 2 | 1:3 |
| 09/04/16 | Santos Laguna | - | CD Veracruz | - | - | - | 2:0 |
Mexico