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| 1st(1st leg) | Vaca Díez | - | Independiente Petrolero | 1:2 | ||
| 2nd (2nd leg) | Independiente Petrolero | - | Vaca Díez | 3:1 | ||
| 1st(1st leg): 16/12/2020 19:00 | 2nd (2nd leg): 20/12/2020 19:30 | Winner: Independiente Petrolero | ||||
| 1st(1st leg) | Fancesa | - | Real Tomayapo | 3:1 | ||
| 2nd (2nd leg) | Real Tomayapo | - | Fancesa | 5:4 pso | ||
| 1st(1st leg): 16/12/2020 19:30 | 2nd (2nd leg): 20/12/2020 19:30 | Winner: Real Tomayapo | ||||
