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| 1st(1st leg) | The Strongest | - | Atlético Palmaflor | 2:1 (1:1) | ||
| 2nd (2nd leg) | Atlético Palmaflor | - | The Strongest | 1:2 (0:0) | ||
| 1st(1st leg): 04/06/2022 20:00 | 2nd (2nd leg): 08/06/2022 21:00 | Winner: The Strongest | ||||
| 1st(1st leg) | Blooming | - | Bolívar | 2:3 (0:0) | ||
| 2nd (2nd leg) | Bolívar | - | Blooming | 4:0 (1:0) | ||
| 1st(1st leg): 05/06/2022 20:00 | 2nd (2nd leg): 09/06/2022 01:00 | Winner: Bolívar | ||||
