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| 18/08/2021 | 22:00 | Colo-Colo | - | Unión Española | 4:0 (1:0) | |
| 19/08/2021 | 00:30 | Everton | - | Coquimbo Unido | 2:1 (0:0) | |
| 01/09/2021 | 21:30 | Coquimbo Unido | - | Everton | 0:0 (0:0) | |
| 02/09/2021 | 00:00 | Unión Española | - | Colo-Colo | 2:3 (1:2) |
|
|
|
|
| 18/08/2021 | 22:00 | Colo-Colo | - | Unión Española | 4:0 (1:0) | |
| 19/08/2021 | 00:30 | Everton | - | Coquimbo Unido | 2:1 (0:0) | |
| 01/09/2021 | 21:30 | Coquimbo Unido | - | Everton | 0:0 (0:0) | |
| 02/09/2021 | 00:00 | Unión Española | - | Colo-Colo | 2:3 (1:2) |
