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| 1st(1st leg) | Huachipato | - | Audax Italiano | 2:1 (1:1) | ||
| 2nd (2nd leg) | Audax Italiano | - | Huachipato | 2:0 (1:0) | ||
| 1st(1st leg): 09/12/2010 | 2nd (2nd leg): 12/12/2010 | Winner: Audax Italiano | ||||
| 1st(1st leg) | Unión Española | - | Universidad de Chile | 0:0 (0:0) | ||
| 2nd (2nd leg) | Universidad de Chile | - | Unión Española | 1:4 (0:2) | ||
| 1st(1st leg): 09/12/2010 | 2nd (2nd leg): 12/12/2010 | Winner: Unión Española | ||||
