 |
 |
|
|
| 1st(1st leg) | Atlético Junior | - | Millonarios | 3:2 (3:1) | ||
| 2nd (2nd leg) | Millonarios | - | Atlético Junior | 2:0 (2:0) | ||
| 1st(1st leg): 10/06/2021 22:00 | 2nd (2nd leg): 13/06/2021 19:30 | Winner: Millonarios | ||||
| 1st(1st leg) | Deportes Tolima | - | La Equidad | 1:1 (1:1) | ||
| 2nd (2nd leg) | La Equidad | - | Deportes Tolima | 1:2 (0:1) | ||
| 1st(1st leg): 11/06/2021 00:05 | 2nd (2nd leg): 15/06/2021 01:00 | Winner: Deportes Tolima | ||||
