1st(1st leg) Independiente Medellín - Deportivo Pereira 1:1 (1:1)
2nd (2nd leg) Deportivo Pereira - Independiente Medellín 4:3 (0:0, 0:0) pso
1st(1st leg): 04/12/2022 23:00 2nd (2nd leg): 08/12/2022 00:00 Winner: Deportivo Pereira
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