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| 1st(1st leg) | Seattle Sounders | - | Santos Laguna | 0:1 (0:0) | ||
| 2nd (2nd leg) | Santos Laguna | - | Seattle Sounders | 1:1 (1:0) | ||
| 1st(1st leg): 03/04/2013 03:00 | 2nd (2nd leg): 10/04/2013 01:00 | Winner: Santos Laguna | ||||
| 1st(1st leg) | Los Angeles Galaxy | - | CF Monterrey | 1:2 (1:0) | ||
| 2nd (2nd leg) | CF Monterrey | - | Los Angeles Galaxy | 1:0 (0:0) | ||
| 1st(1st leg): 04/04/2013 03:00 | 2nd (2nd leg): 11/04/2013 03:00 | Winner: CF Monterrey | ||||
