 |
| 1st(1st leg) | Joe Public FC | - | New England Revolution | 2:1 | ||
| 2nd (2nd leg) | New England Revolution | - | Joe Public FC | 0:4 | ||
| 1st(1st leg): 27/08/2008 01:00 | 2nd (2nd leg): 03/09/2008 01:00 | Winner: Joe Public FC | ||||
| 1st(1st leg) | Tauro FC | - | CD Chivas | 2:0 | ||
| 2nd (2nd leg) | CD Chivas | - | Tauro FC | 1:1 | ||
| 1st(1st leg): 27/08/2008 01:00 | 2nd (2nd leg): 03/09/2008 03:05 | Winner: Tauro FC | ||||
| 1st(1st leg) | Cruz Azul | - | Hankook Verdes | 6:0 | ||
| 2nd (2nd leg) | Hankook Verdes | - | Cruz Azul | 0:6 | ||
| 1st(1st leg): 27/08/2008 03:00 | 2nd (2nd leg): 04/09/2008 03:00 | Winner: Cruz Azul | ||||
| 1st(1st leg) | CF Montréal | - | Real Estelí FC | 1:0 | ||
| 2nd (2nd leg) | Real Estelí FC | - | CF Montréal | 0:0 | ||
| 1st(1st leg): 28/08/2008 01:00 | 2nd (2nd leg): 03/09/2008 03:00 | Winner: CF Montréal | ||||
| 1st(1st leg) | LD Alajuelense | - | Puerto Rico Islanders | 1:1 | ||
| 2nd (2nd leg) | Puerto Rico Islanders | - | LD Alajuelense | 2:1 | ||
| 1st(1st leg): 28/08/2008 03:00 | 2nd (2nd leg): 04/09/2008 01:00 | Winner: Puerto Rico Islanders | ||||
| 1st(1st leg) | Isidro Metapán | - | Marathón | 2:2 | ||
| 2nd (2nd leg) | Marathón | - | Isidro Metapán | 2:1 | ||
| 1st(1st leg): 28/08/2008 03:00 | 2nd (2nd leg): 04/09/2008 05:00 | Winner: Marathón | ||||
| 1st(1st leg) | Harbour View | - | Pumas UNAM | dnp | ||
| 2nd (2nd leg) | Pumas UNAM | - | Harbour View | 3:0 | ||
| 1st(1st leg): 29/08/2008 02:00 | 2nd (2nd leg): 05/09/2008 05:00 | Winner: Pumas UNAM | ||||
| 1st(1st leg) | Deportivo Jalapa | - | San Francisco FC | 1:0 | ||
| 2nd (2nd leg) | San Francisco FC | - | Deportivo Jalapa | 5:0 | ||
| 1st(1st leg): 29/08/2008 05:00 | 2nd (2nd leg): 05/09/2008 02:00 | Winner: San Francisco FC | ||||
