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| 1st(1st leg) | AE Lárissa | - | Akratitos Liosion | 1:0 | ||
| 2nd (2nd leg) | Akratitos Liosion | - | AE Lárissa | 0:1 | ||
| 1st(1st leg): 31/01/2006 | 2nd (2nd leg): 08/02/2006 | Winner: AE Lárissa | ||||
| 1st(1st leg) | Ethnikos Asteras | - | Agrotikos Asteras | 1:1 | ||
| 2nd (2nd leg) | Agrotikos Asteras | - | Ethnikos Asteras | 4:0 | ||
| 1st(1st leg): 01/02/2006 | 2nd (2nd leg): 08/02/2006 | Winner: Agrotikos Asteras | ||||
| 1st(1st leg) | Olympiakos Piraeus | - | Skoda Xanthi | 1:1 | ||
| 2nd (2nd leg) | Skoda Xanthi | - | Olympiakos Piraeus | 0:1 | ||
| 1st(1st leg): 02/02/2006 | 2nd (2nd leg): 09/02/2006 | Winner: Olympiakos Piraeus | ||||
| 1st(1st leg) | Niki Volou FC | - | AEK Athen | 0:0 | ||
| 2nd (2nd leg) | AEK Athen | - | Niki Volou FC | 2:0 | ||
| 1st(1st leg): 07/02/2006 | 2nd (2nd leg): 22/02/2006 | Winner: AEK Athen | ||||
