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| 1st(1st leg) | UANL Tigres | - | CF América | 2:0 (1:0) | ||
| 2nd (2nd leg) | CF América | - | UANL Tigres | 1:3 (1:1) | ||
| 1st(1st leg): 03/05/2019 03:00 | 2nd (2nd leg): 05/05/2019 22:00 | Winner: UANL Tigres | ||||
| 1st(1st leg) | CF Pachuca | - | CF Monterrey | 3:2 (1:0) | ||
| 2nd (2nd leg) | CF Monterrey | - | CF Pachuca | 1:0 (1:0) | ||
| 1st(1st leg): 04/05/2019 01:00 | 2nd (2nd leg): 07/05/2019 03:00 | Winner: CF Monterrey | ||||
