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| 1st(1st leg) | Deportivo Guadalajara | - | Pumas UNAM | 3:2 (1:0) | ||
| 2nd (2nd leg) | Pumas UNAM | - | Deportivo Guadalajara | 1:1 (0:1) | ||
| 1st(1st leg): 10/11/2022 16:00 | 2nd (2nd leg): 13/11/2022 23:00 | Winner: Deportivo Guadalajara | ||||
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| 1st(1st leg) | Deportivo Guadalajara | - | Pumas UNAM | 3:2 (1:0) | ||
| 2nd (2nd leg) | Pumas UNAM | - | Deportivo Guadalajara | 1:1 (0:1) | ||
| 1st(1st leg): 10/11/2022 16:00 | 2nd (2nd leg): 13/11/2022 23:00 | Winner: Deportivo Guadalajara | ||||
