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| 1st(1st leg) | Cruz Azul | - | Jaguares Chiapas | 2:1 (2:0) | ||
| 2nd (2nd leg) | Jaguares Chiapas | - | Cruz Azul | 2:2 (0:2) | ||
| 1st(1st leg): 26/05/2004 23:00 | 2nd (2nd leg): 29/05/2004 21:00 | Winner: Cruz Azul | ||||
| 1st(1st leg) | Atlante | - | Deportivo Guadalajara | 2:0 (1:0) | ||
| 2nd (2nd leg) | Deportivo Guadalajara | - | Atlante | 3:1 (0:1) | ||
| 1st(1st leg): 27/05/2004 02:45 | 2nd (2nd leg): 30/05/2004 01:00 | Winner: Atlante | ||||
| 1st(1st leg) | Deportivo Toluca | - | CF América | 3:2 (1:1) | ||
| 2nd (2nd leg) | CF América | - | Deportivo Toluca | 0:1 (0:0) | ||
| 1st(1st leg): 27/05/2004 21:00 | 2nd (2nd leg): 31/05/2004 00:00 | Winner: Deportivo Toluca | ||||
| 1st(1st leg) | Atlas Guadalajara | - | Pumas UNAM | 1:2 (0:2) | ||
| 2nd (2nd leg) | Pumas UNAM | - | Atlas Guadalajara | 3:1 (1:0) | ||
| 1st(1st leg): 28/05/2004 02:45 | 2nd (2nd leg): 30/05/2004 18:00 | Winner: Pumas UNAM | ||||
