 |
 |
|
|
| 26/02/2021 | 03:00 | Atlético San Luis | - | UANL Tigres | 2:2 (1:1) | |
| 27/02/2021 | 01:30 | Puebla FC | - | Club Necaxa | 1:0 (0:0) | |
| 03:30 | Mazatlán FC | - | Gallos Blancos | 3:0 (2:0) | ||
| 23:00 | Deportivo Toluca | - | Atlas Guadalajara | 0:0 (0:0) | ||
| 28/02/2021 | 01:00 | CF América | - | CF Pachuca | 2:0 (2:0) | |
| 03:00 | Club León | - | Cruz Azul | 0:1 (0:0) | ||
| 23:00 | CF Monterrey | - | Club Tijuana | 1:1 (1:0) | ||
| 01/03/2021 | 01:06 | Santos Laguna | - | FC Juárez | 3:2 (2:0) | |
| 03:00 | Deportivo Guadalajara | - | Pumas UNAM | 2:1 (2:1) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Cruz Azul | 8 | 6 | 0 | 2 | 13:5 | 8 | 18 |
| 2 |
|
CF América | 8 | 5 | 1 | 2 | 10:7 | 3 | 16 |
| 3 |
|
Santos Laguna | 8 | 4 | 3 | 1 | 9:5 | 4 | 15 |
| 4 |
|
Deportivo Toluca | 8 | 4 | 2 | 2 | 15:9 | 6 | 14 |
| 5 |
|
UANL Tigres | 8 | 4 | 2 | 2 | 13:11 | 2 | 14 |
| 6 |
|
Club Tijuana | 8 | 3 | 4 | 1 | 11:8 | 3 | 13 |
| 7 |
|
CF Monterrey | 8 | 3 | 4 | 1 | 7:4 | 3 | 13 |
| 8 |
|
Puebla FC | 8 | 3 | 3 | 2 | 8:4 | 4 | 12 |
| 9 |
|
Atlético San Luis | 8 | 3 | 2 | 3 | 13:11 | 2 | 11 |
| 10 |
|
Deportivo Guadalajara | 8 | 2 | 4 | 2 | 12:12 | 0 | 10 |
| 11 |
|
Gallos Blancos | 8 | 3 | 1 | 4 | 10:14 | -4 | 10 |
| 12 |
|
Mazatlán FC | 8 | 3 | 1 | 4 | 8:13 | -5 | 10 |
| 13 |
|
Atlas Guadalajara | 8 | 2 | 3 | 3 | 5:6 | -1 | 9 |
| 14 |
|
Club León | 8 | 2 | 2 | 4 | 6:10 | -4 | 8 |
| 15 |
|
FC Juárez | 8 | 2 | 2 | 4 | 8:14 | -6 | 8 |
| 16 |
|
Club Necaxa | 8 | 1 | 3 | 4 | 7:12 | -5 | 6 |
| 17 |
|
Pumas UNAM | 8 | 1 | 2 | 5 | 4:7 | -3 | 5 |
| 18 |
|
CF Pachuca | 8 | 0 | 3 | 5 | 3:10 | -7 | 3 |
| Playoffs | |
| Playoffs |
