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| 1st(1st leg) | Deportivo Guadalajara | - | Club Necaxa | 2:3 (1:1) | ||
| 2nd (2nd leg) | Club Necaxa | - | Deportivo Guadalajara | 2:4 (0:1, 1:2, 1:2) pso | ||
| 1st(1st leg): 25/05/2022 16:00 | 2nd (2nd leg): 28/05/2022 15:00 | Winner: Deportivo Guadalajara | ||||
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| 1st(1st leg) | Deportivo Guadalajara | - | Club Necaxa | 2:3 (1:1) | ||
| 2nd (2nd leg) | Club Necaxa | - | Deportivo Guadalajara | 2:4 (0:1, 1:2, 1:2) pso | ||
| 1st(1st leg): 25/05/2022 16:00 | 2nd (2nd leg): 28/05/2022 15:00 | Winner: Deportivo Guadalajara | ||||
