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| 1st(1st leg) | Atlas Guadalajara | - | Club León | 1:2 (0:0) | ||
| 2nd (2nd leg) | Club León | - | Atlas Guadalajara | 1:1 (0:0) | ||
| 1st(1st leg): 05/12/2018 15:00 | 2nd (2nd leg): 08/12/2018 16:00 | Winner: Club León | ||||
| 1st(1st leg) | CF Monterrey | - | Deportivo Guadalajara | 0:0 (0:0) | ||
| 2nd (2nd leg) | Deportivo Guadalajara | - | CF Monterrey | 3:0 (0:0) | ||
| 1st(1st leg): 05/12/2018 16:00 | 2nd (2nd leg): 08/12/2018 18:00 | Winner: Deportivo Guadalajara | ||||
