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| 30/10/2021 | 11:00 | Vitesse | - | NAC Breda | 1:1 | |
| 12:00 | Twente/Heracles | - | ADO Den Haag | 0:3 | ||
| 13:45 | NEC Nijmegen | - | FC Volendam | 3:1 | ||
| 14:00 | Amsterdamsche FC | - | FC Groningen | 2:2 |
| » Tables | Home | Away | First round | Second round | First half | Second half |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Groningen | 8 | 5 | 3 | 0 | 17:6 | 11 | 18 |
| 2 |
|
NAC Breda | 8 | 5 | 3 | 0 | 18:9 | 9 | 18 |
| 3 |
|
Twente/Heracles | 8 | 4 | 0 | 4 | 24:15 | 9 | 12 |
| 4 |
|
Amsterdamsche FC | 8 | 3 | 3 | 2 | 18:21 | -3 | 12 |
| 5 |
|
ADO Den Haag | 8 | 3 | 2 | 3 | 13:9 | 4 | 11 |
| 6 |
|
NEC Nijmegen | 8 | 3 | 1 | 4 | 20:22 | -2 | 10 |
| 7 |
|
Vitesse | 8 | 2 | 1 | 5 | 12:18 | -6 | 7 |
| 8 |
|
FC Volendam | 8 | 0 | 1 | 7 | 7:29 | -22 | 1 |
| Promotion | |
| Relegation |
