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| 02/10/2021 | 13:30 | Vitesse | - | De Graafschap | 1:1 (0:0) | |
| 14:00 | Roda JC Kerkrade | - | Willem II | 1:0 | ||
| 14:15 | Alphense Boys | - | PEC Zwolle | 0:3 | ||
| 14:30 | FC Emmen | - | SBV Excelsior | 1:0 |
| » Tables | Home | Away | First round | Second round | First half | Second half |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Willem II | 5 | 3 | 1 | 1 | 11:7 | 4 | 10 |
| 2 |
|
PEC Zwolle | 5 | 3 | 1 | 1 | 8:4 | 4 | 10 |
| 3 |
|
Alphense Boys | 5 | 3 | 0 | 2 | 8:10 | -2 | 9 |
| 4 |
|
FC Emmen | 5 | 2 | 2 | 1 | 10:8 | 2 | 8 |
| 5 |
|
SBV Excelsior | 5 | 2 | 0 | 3 | 3:4 | -1 | 6 |
| 6 |
|
Roda JC Kerkrade | 5 | 1 | 2 | 2 | 7:9 | -2 | 5 |
| 7 |
|
Vitesse | 5 | 1 | 1 | 3 | 6:9 | -3 | 4 |
| 8 |
|
De Graafschap | 5 | 0 | 3 | 2 | 6:8 | -2 | 3 |
| Promotion | |
| Relegation |
