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| 06/05/2022 | 09:00 | Krylia Sovetov | - | Lokomotiv Moskva | 1:3 (0:2) | |
| 09:00 | Dinamo Moskva | - | Zenit St. Petersburg | 0:3 (0:1) | ||
| 11:00 | Rubin Kazan | - | FK Chertanovo | 0:3 (0:2) | ||
| 12:00 | CSKA Moskva | - | PFC Sochi | 2:0 (1:0) | ||
| 13:30 | Spartak Moskva | - | FK Rostov | 1:1 (0:1) |
| » Tables | Home | Away | First half | Second half |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CSKA Moskva | 26 | 20 | 2 | 4 | 56:21 | 35 | 62 |
| 2 |
|
FK Rostov | 26 | 17 | 5 | 4 | 63:23 | 40 | 56 |
| 3 |
|
Lokomotiv Moskva | 26 | 16 | 4 | 6 | 44:27 | 17 | 52 |
| 4 |
|
Zenit St. Petersburg | 26 | 16 | 1 | 9 | 60:32 | 28 | 49 |
| 5 |
|
FK Chertanovo | 26 | 13 | 5 | 8 | 44:30 | 14 | 44 |
| 6 |
|
Dinamo Moskva | 26 | 13 | 2 | 11 | 45:41 | 4 | 41 |
| 7 |
|
PFC Sochi | 26 | 13 | 2 | 11 | 41:40 | 1 | 41 |
| 8 |
|
Spartak Moskva | 26 | 12 | 4 | 10 | 37:29 | 8 | 40 |
| 9 |
|
Krylia Sovetov | 26 | 11 | 4 | 11 | 32:45 | -13 | 37 |
| 10 |
|
Rubin Kazan | 26 | 10 | 7 | 9 | 47:40 | 7 | 37 |
