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| 1st(1st leg) | FC Winterthur | - | FC Basel 1893 | 1:2 (1:1) | ||
| 2nd (2nd leg) | FC Basel 1893 | - | FC Winterthur | 3:0 (1:0) | ||
| 1st(1st leg): 28/05/2022 12:00 | 2nd (2nd leg): 04/06/2022 15:30 | Winner: FC Basel 1893 | ||||
| 1st(1st leg) | FC Zürich | - | Team Vaud Lausanne | 5:0 (2:0) | ||
| 2nd (2nd leg) | Team Vaud Lausanne | - | FC Zürich | 2:3 (0:2) | ||
| 1st(1st leg): 28/05/2022 13:00 | 2nd (2nd leg): 04/06/2022 13:30 | Winner: FC Zürich | ||||
| 1st(1st leg) | FCO St. Gallen/Wil | - | Servette FC | 2:1 (1:0) | ||
| 2nd (2nd leg) | Servette FC | - | FCO St. Gallen/Wil | 3:1 (0:0) | ||
| 1st(1st leg): 28/05/2022 13:00 | 2nd (2nd leg): 04/06/2022 13:00 | Winner: Servette FC | ||||
| 1st(1st leg) | Team Aargau | - | BSC Young Boys | 1:5 (0:3) | ||
| 2nd (2nd leg) | BSC Young Boys | - | Team Aargau | 3:0 (1:0) | ||
| 1st(1st leg): 28/05/2022 15:00 | 2nd (2nd leg): 04/06/2022 13:00 | Winner: BSC Young Boys | ||||
