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| 17/07/2018 | 16:00 | Tavriya Simferopol (alt) | - | Chaika Petropavlivska Borshchahivka | 1:0 | |
| 18/07/2018 | Naftovik-Ukrnafta | - | Hirnyk Kryvyi Rih | 0:3 dec. | ||
| 15:00 | FC Viktoriya Mykolaivka | - | FK Ternopil | 2:1 | ||
| 15:00 | FC LNZ Cherkasy | - | Polissya Zhytomyr | 4:2 pso | ||
| 15:00 | FC Kalush | - | FK Bukovina | 4:3 pso | ||
| 15:30 | Real Pharma Odessa | - | FK Nyva Vinnytsia | 0:2 | ||
| 15:30 | Enerhiya Nova Kakhovka | - | Kristal Kherson | 0:1 | ||
| 15:30 | FC Nikopol-NPHU | - | Myr Hornostayivka | 1:4 | ||
| 16:00 | FK Podillya-Khmelnitskiy | - | Metalurg Zaporizhya | 0:2 | ||
| 16:00 | NK Veres | - | FC Mynai | 9:10 pso |
