| 1. Round | 26/08/2018 | Xanthi FC | - | Panathinaikos | 0:1 | ||||
| 2. Round | 01/09/2018 | Panathinaikos | - | Lamia | 3:1 | ||||
| 3. Round | 16/09/2018 | AE Lárissa | - | Panathinaikos | 1:3 | ||||
| 5. Round | 29/09/2018 | Panathinaikos | - | PAS Giannina | 2:1 | ||||
| 6. Round | 06/10/2018 | Asteras Tripolis | - | Panathinaikos | 1:1 | ||||
| 9. Round | 03/11/2018 | Panathinaikos | - | AEK Athen | 0:0 | ||||
| 10. Round | 11/11/2018 | Olympiakos Piraeus | - | Panathinaikos | 1:1 | ||||
| 12. Round | 02/12/2018 | Aris Saloniki | - | Panathinaikos | 1:1 | ||||
| 13. Round | 09/12/2018 | OFI Heraklion | - | Panathinaikos | 3:1 | ||||
| 14. Round | 16/12/2018 | Panathinaikos | - | Atromitos | 1:0 | ||||
| 21. Round | 16/02/2019 | Panathinaikos | - | Asteras Tripolis | 1:0 | ||||
| 22. Round | 24/02/2019 | Panionios GSS | - | Panathinaikos | 2:0 | ||||
| 23. Round | 03/03/2019 | Panathinaikos | - | PAOK Saloniki | 0:2 | ||||
| 27. Round | 06/04/2019 | Panathinaikos | - | Aris Saloniki | 2:0 |  |
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| 30. Round | 05/05/2019 | Panathinaikos | - | Panetolikos | 4:0 |
Greece