| 3. Round | 24/08/2008 | Racing Club | - | Independiente | 1:1 | ||||
| 8. Round | 28/09/2008 | Independiente | - | Lanús | 0:2 | ||||
| 9. Round | 05/10/2008 | Huracán | - | Independiente | 1:0 | ||||
| 10. Round | 18/10/2008 | Colón de Santa Fe | - | Independiente | 1:2 | ||||
| 11. Round | 26/10/2008 | Independiente | - | Argentinos Juniors | 1:1 |  |
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| 13. Round | 31/10/2008 | Independiente | - | Godoy Cruz | 1:1 | |
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| 14. Round | 08/11/2008 | Estudiantes | - | Independiente | 1:0 | ||||
| 15. Round | 16/11/2008 | Independiente | - | River Plate | 0:1 | |
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| 16. Round | 22/11/2008 | Rosario Central | - | Independiente | 1:2 | ||||
| 17. Round | 28/11/2008 | Independiente | - | Banfield | 0:1 | ||||
| 18. Round | 07/12/2008 | San Lorenzo | - | Independiente | 4:1 | ||||
| 19. Round | 14/12/2008 | Independiente | - | Arsenal de Sarandí | 1:2 |
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