| 1. Round | 08/02/2008 | San Lorenzo | - | Newell's Old Boys | 0:2 | ||||
| 2. Round | 16/02/2008 | San Lorenzo | - | San Martín de San Juan | 0:1 | ||||
| 3. Round | 24/02/2008 | River Plate | - | San Lorenzo | 2:0 |  |
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| 4. Round | 01/03/2008 | San Lorenzo | - | Estudiantes | 3:1 |  |
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| 5. Round | 07/03/2008 | Racing Club | - | San Lorenzo | 0:1 | ||||
| 7. Round | 21/03/2008 | Arsenal de Sarandí | - | San Lorenzo | 0:1 | ||||
| 10. Round | 13/04/2008 | San Lorenzo | - | Rosario Central | 3:1 | |
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| 6. Round | 23/04/2008 | San Lorenzo | - | Vélez Sarsfield | 1:0 | ||||
| 15. Round | 18/05/2008 | Huracán | - | San Lorenzo | 0:0 | ||||
| 17. Round | 01/06/2008 | Olimpo de Bahía Blanca | - | San Lorenzo | 3:2 | ||||
| 18. Round | 08/06/2008 | San Lorenzo | - | Banfield | 3:2 | ||||
| 19. Round | 22/06/2008 | Gimnasia de Jujuy | - | San Lorenzo | 2:2 |
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