| 15. Round | 15/12/2018 | FC Augsburg | - | FC Schalke 04 | 1:1 | ||||
| 17. Round | 22/12/2018 | VfB Stuttgart | - | FC Schalke 04 | 1:3 |  |
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| 18. Round | 20/01/2019 | FC Schalke 04 | - | VfL Wolfsburg | 2:1 | ||||
| 19. Round | 25/01/2019 | Hertha BSC | - | FC Schalke 04 | 2:2 | ||||
| 21. Round | 09/02/2019 | Bayern München | - | FC Schalke 04 | 3:1 | |
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| 22. Round | 16/02/2019 | FC Schalke 04 | - | SC Freiburg | 0:0 | ||||
| 23. Round | 23/02/2019 | 1. FSV Mainz 05 | - | FC Schalke 04 | 3:0 | ||||
| 24. Round | 02/03/2019 | FC Schalke 04 | - | Fortuna Düsseldorf | 0:4 | ||||
| 25. Round | 08/03/2019 | Werder Bremen | - | FC Schalke 04 | 4:2 | ||||
| 26. Round | 16/03/2019 | FC Schalke 04 | - | RB Leipzig | 0:1 | ||||
| 27. Round | 31/03/2019 | Hannover 96 | - | FC Schalke 04 | 0:1 | ||||
| 28. Round | 06/04/2019 | FC Schalke 04 | - | Eintracht Frankfurt | 1:2 | ||||
| 32. Round | 05/05/2019 | FC Schalke 04 | - | FC Augsburg | 0:0 |
Germany