| 1. Round | 14/07/2019 | San Lorenzo | - | Libertad | 0:1 | ||||
| 2. Round | 23/07/2019 | Sportivo Luqueño | - | San Lorenzo | 1:3 |  |
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| 3. Round | 28/07/2019 | San Lorenzo | - | Cerro Porteño | 2:1 | ||||
| 4. Round | 03/08/2019 | Deportivo Santaní | - | San Lorenzo | 1:1 | ||||
| 5. Round | 10/08/2019 | San Lorenzo | - | Deportivo Capiatá | 1:1 | ||||
| 6. Round | 16/08/2019 | San Lorenzo | - | General Díaz | 1:1 | |
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| 7. Round | 24/08/2019 | Guaraní | - | San Lorenzo | 3:1 | ||||
| 8. Round | 01/09/2019 | San Lorenzo | - | Sol de América | 1:2 | ||||
| 11. Round | 24/09/2019 | River Plate | - | San Lorenzo | 0:0 | ||||
| 18. Round | 10/11/2019 | San Lorenzo | - | Guaraní | 0:0 | ||||
| 17. Round | 22/11/2019 | General Díaz | - | San Lorenzo | 1:1 | ||||
| 20. Round | 01/12/2019 | San Lorenzo | - | Club Olimpia | 1:4 | |
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| 21. Round | 09/12/2019 | Club Nacional | - | San Lorenzo | 4:2 | |
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| 22. Round | 15/12/2019 | San Lorenzo | - | River Plate | 2:0 | |
Argentina