| 2. Round | 20/03/2021 | Barracas Central | - | Defensores de Belgrano | 1:1 | ||||
| 3. Round | 27/03/2021 | Ramón Santamarina | - | Barracas Central | 1:1 |  |
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| 5. Round | 11/04/2021 | Güemes de SdE | - | Barracas Central | 3:0 | ||||
| 6. Round | 17/04/2021 | Barracas Central | - | Deportivo Morón | 1:0 | ||||
| 12. Round | 17/06/2021 | Independiente Rivadavia | - | Barracas Central | 0:0 | ||||
| 13. Round | 22/06/2021 | Barracas Central | - | Atlético Rafaela | 2:1 | ||||
| 14. Round | 27/06/2021 | Guillermo Brown | - | Barracas Central | 0:1 | ||||
| 16. Round | 12/07/2021 | San Martín de San Juan | - | Barracas Central | 2:3 |  |
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| 17. Round | 17/07/2021 | Barracas Central | - | Villa Dálmine | 1:0 | ||||
| 32. Round | 31/10/2021 | Brown de Adrogué | - | Barracas Central | 1:2 | ||||
| 33. Round | 07/11/2021 | Barracas Central | - | San Martín de San Juan | 3:0 |
Argentina