| 7. Round | 14/11/2021 | Union Lorraine de Plantières | - | AS Nancy Lorraine | 1:3 |  |
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| 8. Round | 27/11/2021 | FC Soleil Bischheim | - | AS Nancy Lorraine | 0:1 | ||||
| 9. Round | 18/12/2021 | ESTAC Troyes | - | AS Nancy Lorraine | 2:4 pso | |
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| 10. Round | 02/01/2022 | AS Nancy Lorraine | - | Stade Rennais | 4:3 pso | ||||
| Round of 16 | 29/01/2022 | AS Nancy Lorraine | - | Amiens SC | 0:2 |
France