| 6. Round | 22/09/2018 | Elazığspor | - | Karabükspor | 4:0 | ||||
| 10. Round | 27/10/2018 | Adanaspor | - | Karabükspor | 4:0 | ||||
| 11. Round | 04/11/2018 | Karabükspor | - | Boluspor | 0:2 |  |
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| 12. Round | 10/11/2018 | Giresunspor | - | Karabükspor | 4:0 | ||||
| 13. Round | 23/11/2018 | Karabükspor | - | Balıkesirspor | 1:2 | ||||
| 14. Round | 01/12/2018 | Gençlerbirliği | - | Karabükspor | 6:0 | ||||
| 15. Round | 08/12/2018 | Karabükspor | - | İstanbulspor AŞ | 1:1 | |
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| 16. Round | 15/12/2018 | Karabükspor | - | Denizlispor | 2:3 | ||||
| 17. Round | 22/12/2018 | Gazişehir Gaziantep FK | - | Karabükspor | 6:1 | |
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| 18. Round | 18/01/2019 | Adana Demirspor | - | Karabükspor | 1:0 | |
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| 20. Round | 02/02/2019 | Altınordu FK | - | Karabükspor | 6:0 | ||||
| 21. Round | 09/02/2019 | Karabükspor | - | Eskişehirspor | 0:4 | |
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| 22. Round | 17/02/2019 | Osmanlıspor FK | - | Karabükspor | 3:0 | |
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| 23. Round | 24/02/2019 | Karabükspor | - | Elazığspor | 1:3 |  |
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| 25. Round | 09/03/2019 | Karabükspor | - | Afjet Afyonspor | 0:4 | ||||
| 26. Round | 17/03/2019 | Altay Izmir | - | Karabükspor | 4:0 | ||||
| 27. Round | 02/04/2019 | Karabükspor | - | Adanaspor | 0:1 | ||||
| 28. Round | 06/04/2019 | Boluspor | - | Karabükspor | 4:0 | |
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| 29. Round | 14/04/2019 | Karabükspor | - | Giresunspor | 0:0 |
Turkey