| 1. Round | 13/08/2000 | İstanbulspor AŞ | - | Adanaspor | 1:6 | ||||
| 5. Round | 17/09/2000 | Yozgatspor | - | Adanaspor | 4:1 | ||||
| 6. Round | 23/09/2000 | Adanaspor | - | Antalyaspor | 1:1 | ||||
| 7. Round | 01/10/2000 | Adanaspor | - | Çaykur Rizespor | 1:0 | ||||
| 8. Round | 13/10/2000 | Adanaspor | - | Denizlispor | 2:3 |  |
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| 9. Round | 20/10/2000 | Adanaspor | - | Fenerbahçe | 1:1 |  |
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| 10. Round | 28/10/2000 | MKE Ankaragücü | - | Adanaspor | 4:0 | ||||
| 11. Round | 05/11/2000 | Adanaspor | - | Gaziantepspor | 0:1 | ||||
| 12. Round | 12/11/2000 | Trabzonspor | - | Adanaspor | 3:3 | ||||
| 13. Round | 18/11/2000 | Adanaspor | - | Galatasaray | 1:2 | |
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| 14. Round | 25/11/2000 | Erzurumspor (1968-2015) | - | Adanaspor | 2:0 | ||||
| 17. Round | 17/12/2000 | Adanaspor | - | Kocaelispor | 4:4 | |
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| 18. Round | 22/12/2000 | Adanaspor | - | İstanbulspor AŞ | 2:2 | ||||
| 23. Round | 03/03/2001 | Antalyaspor | - | Adanaspor | 2:1 | ||||
| 24. Round | 11/03/2001 | Çaykur Rizespor | - | Adanaspor | 4:2 | ||||
| 25. Round | 18/03/2001 | Denizlispor | - | Adanaspor | 4:2 | ||||
| 27. Round | 07/04/2001 | Adanaspor | - | MKE Ankaragücü | 1:3 |
Turkey