| 1. Round | 10/08/2015 | Tottenham Hotspur U21 | - | Everton FC U21 | 4:1 | ||||
| 2. Round | 14/08/2015 | Manchester City U21 | - | Tottenham Hotspur U21 | 3:3 | ||||
| 3. Round | 23/08/2015 | Sunderland AFC U21 | - | Tottenham Hotspur U21 | 1:0 |  |
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| 4. Round | 14/09/2015 | Tottenham Hotspur U21 | - | Reading FC U21 | 1:4 | ||||
| 5. Round | 21/09/2015 | Tottenham Hotspur U21 | - | Leicester City U21 | 7:4 |  |
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| 8. Round | 23/10/2015 | Tottenham Hotspur U21 | - | Liverpool FC U21 | 1:1 | ||||
| 9. Round | 30/10/2015 | Chelsea FC U21 | - | Tottenham Hotspur U21 | 1:3 | ||||
| 10. Round | 07/12/2015 | Tottenham Hotspur U21 | - | Southampton FC U21 | 0:2 | ||||
| 13. Round | 14/12/2015 | Everton FC U21 | - | Tottenham Hotspur U21 | 1:1 | ||||
| 19. Round | 04/01/2016 | Manchester United U21 | - | Tottenham Hotspur U21 | 3:1 | ||||
| 14. Round | 11/01/2016 | Tottenham Hotspur U21 | - | Chelsea FC U21 | 4:5 | ||||
| 15. Round | 25/01/2016 | Liverpool FC U21 | - | Tottenham Hotspur U21 | 2:0 | ||||
| 17. Round | 09/02/2016 | Southampton FC U21 | - | Tottenham Hotspur U21 | 1:1 |
England
