| 5. Round | 12/02/2025 | Newell's Old Boys | - | Defensa y Justicia | 0:1 | ||||
| 6. Round | 16/02/2025 | Newell's Old Boys | - | Rosario Central | 1:2 | ||||
| 7. Round | 24/02/2025 | Barracas Central | - | Newell's Old Boys | 2:0 | ||||
| 8. Round | 04/03/2025 | Atlético Tucumán | - | Newell's Old Boys | 1:2 | ||||
| 9. Round | 10/03/2025 | Newell's Old Boys | - | Belgrano de Córdoba | 0:0 | ||||
| 10. Round | 15/03/2025 | Estudiantes | - | Newell's Old Boys | 1:1 | ||||
| 11. Round | 30/03/2025 | Newell's Old Boys | - | Boca Juniors | 2:0 | ||||
| 12. Round | 08/04/2025 | Tigre | - | Newell's Old Boys | 0:2 | ||||
| 13. Round | 12/04/2025 | Newell's Old Boys | - | Argentinos Juniors | 0:0 | ||||
| 14. Round | 19/04/2025 | Unión de Santa Fe | - | Newell's Old Boys | 1:1 |  |
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| 15. Round | 29/04/2025 | Newell's Old Boys | - | Huracán | 2:0 | ||||
| 16. Round | 02/05/2025 | Racing Club | - | Newell's Old Boys | 1:0 |
Paraguay