| 1. Round | 14/02/2021 | Boca Juniors | - | Gimnasia de La Plata | 2:2 |  |
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| 2. Round | 22/02/2021 | Newell's Old Boys | - | Boca Juniors | 0:1 | |
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| 3. Round | 01/03/2021 | Boca Juniors | - | Sarmiento de Junín | 1:1 | ||||
| 5. Round | 14/03/2021 | Boca Juniors | - | River Plate | 1:1 | ||||
| 6. Round | 22/03/2021 | Boca Juniors | - | Talleres de Córdoba | 1:2 |  |
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| 7. Round | 29/03/2021 | Independiente | - | Boca Juniors | 1:1 | |
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| 8. Round | 03/04/2021 | Boca Juniors | - | Defensa y Justicia | 2:1 | ||||
| 9. Round | 11/04/2021 | Unión de Santa Fe | - | Boca Juniors | 1:0 | ||||
| 10. Round | 17/04/2021 | Boca Juniors | - | Atlético Tucumán | 3:1 | ||||
| 11. Round | 24/04/2021 | Huracán | - | Boca Juniors | 0:2 | ||||
| 12. Round | 02/05/2021 | Boca Juniors | - | Lanús | 1:0 | |
Argentina
Italy