| 3. Round | 15/06/2022 | Banfield | - | Central Córdoba SdE | 2:1 | ||||
| 4. Round | 22/06/2022 | Central Córdoba SdE | - | San Lorenzo | 0:2 | ||||
| 5. Round | 25/06/2022 | Talleres de Córdoba | - | Central Córdoba SdE | 0:2 |  |
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| 6. Round | 01/07/2022 | Central Córdoba SdE | - | Argentinos Juniors | 1:2 | ||||
| 10. Round | 24/07/2022 | Central Córdoba SdE | - | Racing Club | 1:3 | ||||
| 11. Round | 01/08/2022 | Rosario Central | - | Central Córdoba SdE | 0:3 |  |
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| 12. Round | 08/08/2022 | Central Córdoba SdE | - | Defensa y Justicia | 1:0 | ||||
| 13. Round | 12/08/2022 | Atlético Tucumán | - | Central Córdoba SdE | 1:0 | ||||
| 14. Round | 16/08/2022 | Central Córdoba SdE | - | Colón de Santa Fe | 3:0 | |
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| 22. Round | 01/10/2022 | Central Córdoba SdE | - | Sarmiento de Junín | 0:0 | ||||
| 23. Round | 06/10/2022 | Independiente | - | Central Córdoba SdE | 1:2 | ||||
| 24. Round | 11/10/2022 | Central Córdoba SdE | - | Newell's Old Boys | 0:3 | ||||
| 25. Round | 15/10/2022 | Arsenal de Sarandí | - | Central Córdoba SdE | 2:0 |
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