| 3. Round | 07/08/2021 | Deportivo Guadalajara [U18] | - | FC Juárez [U18] | 1:2 | ||||
| 4. Round | 13/08/2021 | FC Juárez [U18] | - | Club Tijuana [U18] | 3:2 | ||||
| 5. Round | 18/08/2021 | FC Juárez [U18] | - | CF América [U18] | 2:2 | ||||
| 12. Round | 01/10/2021 | FC Juárez [U18] | - | CF Monterrey [U18] | 3:0 | ||||
| 16. Round | 29/10/2021 | FC Juárez [U18] | - | Puebla FC [U18] | 0:2 | ||||
| 17. Round | 06/11/2021 | UANL Tigres [U18] | - | FC Juárez [U18] | 2:0 |
Mexico