| 1. Round | 13/02/2021 | Unión de Santa Fe | - | Atlético Tucumán | 2:2 | ||||
| 2. Round | 22/02/2021 | Atlético Tucumán | - | Central Córdoba SdE | 1:2 | ||||
| 3. Round | 02/03/2021 | Atlético Tucumán | - | Huracán | abor. |  |
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| 5. Round | 15/03/2021 | Atlético Tucumán | - | Patronato de Paraná | 4:2 | ||||
| 8. Round | 03/04/2021 | Sarmiento de Junín | - | Atlético Tucumán | 1:2 | ||||
| 9. Round | 13/04/2021 | Atlético Tucumán | - | Vélez Sarsfield | 2:0 |  |
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| 10. Round | 17/04/2021 | Boca Juniors | - | Atlético Tucumán | 3:1 | |
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| 13. Round | 08/05/2021 | Atlético Tucumán | - | Defensa y Justicia | 5:0 |
Argentina