| 10. Round | 03/09/2021 | Vélez Sarsfield II | - | Unión de Santa Fe II | 2:2 | ||||
| 12. Round | 17/09/2021 | Vélez Sarsfield II | - | Aldosivi II | 1:1 | ||||
| 13. Round | 24/09/2021 | Sarmiento de Junín II | - | Vélez Sarsfield II | 0:4 | ||||
| 14. Round | 01/10/2021 | Vélez Sarsfield II | - | Independiente II | 0:0 | ||||
| 16. Round | 13/10/2021 | Vélez Sarsfield II | - | Arsenal de Sarandí II | 1:1 | ||||
| 18. Round | 25/10/2021 | Vélez Sarsfield II | - | Boca Juniors II | 1:2 | ||||
| 22. Round | 25/11/2021 | Vélez Sarsfield II | - | Argentinos Juniors II | 1:1 | ||||
| 24. Round | 06/12/2021 | Vélez Sarsfield II | - | Patronato de Paraná II | 1:0 |
Argentina