| 1. Round | 07/08/2005 | Quilmes | - | Newell's Old Boys | 1:1 | ||||
| 2. Round | 13/08/2005 | Newell's Old Boys | - | Tiro Federal de Rosario | 2:1 |  |
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| 3. Round | 21/08/2005 | River Plate | - | Newell's Old Boys | 2:1 | |
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| 4. Round | 27/08/2005 | Gimnasia de Jujuy | - | Newell's Old Boys | 2:0 | ||||
| 6. Round | 11/09/2005 | Colón de Santa Fe | - | Newell's Old Boys | 1:1 | ||||
| 8. Round | 24/09/2005 | Vélez Sarsfield | - | Newell's Old Boys | 1:0 | ||||
| 9. Round | 01/10/2005 | Newell's Old Boys | - | Estudiantes | 3:2 | ||||
| 14. Round | 13/11/2005 | Lanús | - | Newell's Old Boys | 1:1 | ||||
| 15. Round | 17/11/2005 | Newell's Old Boys | - | Instituto de Córdoba | 5:0 | ||||
| 16. Round | 22/11/2005 | San Lorenzo | - | Newell's Old Boys | 4:2 | |
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