| 19. Round | 08/08/2010 | Santiago Morning | - | Cobresal | 1:1 | ||||
| 20. Round | 15/08/2010 | Santiago Morning | - | Universidad Católica | 0:2 |  |
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| 23. Round | 14/09/2010 | Santiago Morning | - | Universidad de Chile | 1:2 | ||||
| 24. Round | 17/09/2010 | Unión Española | - | Santiago Morning | 2:2 | ||||
| 25. Round | 25/09/2010 | Santiago Morning | - | Everton | 3:0 | ||||
| 26. Round | 03/10/2010 | Universidad de Concepción | - | Santiago Morning | 0:0 | ||||
| 27. Round | 17/10/2010 | Santiago Morning | - | Ñublense | 4:1 | ||||
| 28. Round | 24/10/2010 | Santiago Morning | - | O'Higgins | 2:1 | ||||
| 29. Round | 31/10/2010 | Cobreloa | - | Santiago Morning | 2:1 | ||||
| 30. Round | 07/11/2010 | Santiago Morning | - | San Luis | 2:0 | ||||
| 31. Round | 13/11/2010 | Colo-Colo | - | Santiago Morning | 0:1 | ||||
| 32. Round | 21/11/2010 | Audax Italiano | - | Santiago Morning | 1:0 | ||||
| 33. Round | 28/11/2010 | Santiago Morning | - | Huachipato | 0:3 |
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