| 1. Round | 08/07/2022 | Deportivo Pereira | - | Alianza Petrolera | 1:2 | ||||
| 2. Round | 13/07/2022 | Alianza Petrolera | - | Unión Magdalena | 0:1 | ||||
| 4. Round | 23/07/2022 | Alianza Petrolera | - | Atlético Bucaramanga | 3:1 | ||||
| 7. Round | 13/08/2022 | Cortuluá | - | Alianza Petrolera | 0:2 |  |
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| 8. Round | 20/08/2022 | Alianza Petrolera | - | Deportivo Cali | 4:4 | ||||
| 9. Round | 27/08/2022 | Alianza Petrolera | - | Deportivo Pasto | 0:0 | ||||
| 10. Round | 03/09/2022 | Atlético Bucaramanga | - | Alianza Petrolera | 3:1 |  |
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| 11. Round | 13/09/2022 | Águilas Doradas | - | Alianza Petrolera | 1:0 | ||||
| 15. Round | 01/10/2022 | Independiente Medellín | - | Alianza Petrolera | 3:1 | ||||
| 18. Round | 18/10/2022 | Alianza Petrolera | - | América de Cali | 0:2 | ||||
| 19. Round | 24/10/2022 | Once Caldas | - | Alianza Petrolera | 1:1 |
Colombia