| 3. Round | 13/02/2008 | PSV Eindhoven | - | Helsingborgs IF | 2:0 | ||||
| 3. Round | 21/02/2008 | Helsingborgs IF | - | PSV Eindhoven | 1:2 | ||||
| Round of 16 | 06/03/2008 | Tottenham Hotspur | - | PSV Eindhoven | 0:1 | ||||
| Round of 16 | 12/03/2008 | PSV Eindhoven | - | Tottenham Hotspur | 6:5 pso | ||||
| Quarter-finals | 03/04/2008 | ACF Fiorentina | - | PSV Eindhoven | 1:1 |  |
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| Quarter-finals | 10/04/2008 | PSV Eindhoven | - | ACF Fiorentina | 0:2 |
Netherlands